Type 2 Diabetes Breakthrough  April 2025

Type 2 Diabetes Breakthrough  April 2025

Type 2 Diabetes Breakthrough • April 2025

Leading Scientist:
Activate your "Youth Hormone" and completely stop the hot flashes.

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Scientific References

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  1. Baulieu, E. E. (1996). Dehydroepiandrosterone (DHEA): A fountain of youth? The Journal of Clinical Endocrinology & Metabolism, 81(6). https://pubmed.ncbi.nlm.nih.gov/8784058/
  2. Labrie, F., Bélanger, A., Cusan, L., Gomez, J. L., & Candas, B. (1997). Marked decline in serum concentrations of adrenal C19 sex steroid precursors and conjugated androgen metabolites during aging. The Journal of Clinical Endocrinology & Metabolism, 82(8), 2396–2402.
    https://pubmed.ncbi.nlm.nih.gov/9253307/
  3. Komesaroff, P. A., Black, C. V., Cable, V., & Sudhir, K. (2001). Effects of wild yam extract on menopausal symptoms, lipids, and sex hormones in healthy menopausal women. Climacteric, 4(2), 144-150.
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  4. Genazzani, A. R., Stomati, M., Bernardi, F., Luisi, M., Casarosa, E., Puccetti, S., Genazzani, A. D., Palumbo, M., Luisi, S., & Petraglia, F. (2001). Dehydroepiandrosterone (DHEA) administration positively affects spontaneous and opioid-induced LH and FSH secretion in postmenopause. European Journal of Endocrinology, 144(6), 590–595.
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  5. Morales, A. J., Nolan, J. J., Nelson, J. C., & Yen, S. S. (1994). Effects of replacement dose of dehydroepiandrosterone in men and women of advancing age. The Journal of Clinical Endocrinology & Metabolism, 78(6), 1360–1367. https://pubmed.ncbi.nlm.nih.gov/7515387/
  6. Keenan, D. M., & Veldhuis, J. D. (2004). Age-related reductions in coupled serial pulsatile release of adrenal androgens. American Journal of Physiology-Endocrinology and Metabolism, 287(5), E857–E864.
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  7. Lobo, R. A., Stanczyk, F. Z., Cummings, S., & Speroff, L. (2003). Dehydroepiandrosterone and bone mineral density: Do we need DHEA supplements as an antiaging strategy? The Journal of Clinical Endocrinology & Metabolism, 88(8), 3735–3740. https://pmc.ncbi.nlm.nih.gov/articles/PMC11673555/
  8. Jarry, H., Metten, M., Spengler, B., Christoffel, V., & Wuttke, W. (2005). In vitro effects of the Cimicifuga racemosa extract BNO 1055. Maturitas, 51(4), 399–408. https://pubmed.ncbi.nlm.nih.gov/12609557/
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  10. Booth, N. L., Piersen, C. E., Banuvar, S., Geller, S. E., Shulman, L. P., & Farnsworth, N. R. (2006). Clinical studies of black cohosh (Cimicifuga racemosa, Actaea racemosa) for the treatment of menopausal symptoms. Menopause, 13(2), 251–260. https://pmc.ncbi.nlm.nih.gov/articles/PMC4029542/
  11. Ososki, A. L., & Kennelly, E. J. (2003). Phytoestrogens: A review of the present state of research. Phytotherapy Research, 17(8), 845–869. https://pubmed.ncbi.nlm.nih.gov/13680814/
  12. Tice, J. A., Ettinger, B., Ensrud, K., Wallace, R., Blackwell, T., & Cummings, S. R. (2003). Phytoestrogen supplements for the treatment of hot flashes: The Isoflavone Clover Extract (ICE) Study: A randomized controlled trial. JAMA, 290(2), 207–214. https://doi.org/10.1001/jama.290.2.207 [PMID: 12851279]
  13. Imhof, M., Molero, A., Rössler, A., Motsch, E., & Kreutzer, M. (2006). Improvement of climacteric symptoms by standardized Ginkgo biloba extract in perimenopausal women: A randomized, double-blind, placebo-controlled clinical trial. Phytomedicine, 13(3), 164–171. https://doi.org/10.1016/j.phymed.2004.12.005 [PMID: 16531093]
  14. Wang, H. J., Xia, Y. M., Zhang, J., Zhang, R., Yang, Z. J., Huang, J. Y., ... & Peng, X. C. (2019). Diosgenin ameliorates menopause-induced metabolic syndromes via activation of estrogen receptor alpha. The Journal of Steroid Biochemistry and Molecular Biology, 194, 105418. https://pubmed.ncbi.nlm.nih.gov/31666479/
  15. Choi, S. Y., Lee, S., Choi, W. H., Lee, Y. J., & Lee, B. H. (2009). Effects of diosgenin on skin aging-related genes in human dermal fibroblast cells: Microarray analysis. The Journal of Dermatological Science, 55(3), 189-192. https://pubmed.ncbi.nlm.nih.gov/19428439/
  16. Steels, E., Rao, A., Vitetta, L., & Inder, W. J. (2020). Physiological effects of a proprietary Trigonella foenum-graecum (Fenugreek) extract on menopausal symptoms in otherwise healthy women: A double-blind, randomized, placebo-controlled study. Frontiers in Endocrinology, 11, 558129. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306339/
  17. Nappi, R. E., Malavasi, B., Brundu, B., Facchinetti, F., & Genazzani, A. R. (2014). Efficacy of black cohosh (Cimicifuga racemosa) on menopausal symptoms: An Italian observational study. Gynecological Endocrinology, 30(5), 357–362. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029542/

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